Liver Disease Knowledge and Acceptability of Non-Invasive Liver Fibrosis Assessment among People who Inject Drugs in the Drug and Alcohol Setting: The Liverlife Study

Author: Marshall A, Micallef M, Erratt A, Telenta J, Treloar C, H. Everingham, Jones S, Bath N, How-Chow D, Byrne J, Harvey P, Dunlop A, Jauncey M, Read P, Collie T, Dore G, Grebely J

Theme: Clinical Research Year: 2015

Background: Liver disease burden among people who inject drugs (PWID) is high, yet few strategies to enhance liver disease screening have been evaluated. The aim of this study was to assess factors associated with baseline knowledge of HCV and liver disease, acceptability of transient elastography (TE) assessment (FibroScan®), and willingness to receive HCV treatment among PWID participating in a liver health promotion campaign.

Methods: The LiveRLife campaign involved: 1) educational resource development; 2) resource testing; and 3) implementation. Between May-October 2014, participants were enrolled in an observational cohort study with recruitment from four clinics in Australia [one targeted primary healthcare facility, two opioid substitution treatment clinics, and one medically supervised injecting centre]. Participants received educational material, Clinical Research assessment, TE assessment, dried blood spot testing, and completed a knowledge survey.

Results: Of 253 participants (mean age 43 years), 68% were male, 71% had injected in the past month, and 75% self-reported as HCV positive. Median knowledge score was 16/23. In adjusted analysis, high knowledge (≥16) was associated with Download abstract Download presentation